Substituted 4-(quinolin-2-yl-methoxy)phenyl-acetic acid derivatives and anti-allergic use thereof

US4970215A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Klaus-Helmut Mohrs · Wuppertal, DE
• Siegfried Raddatz · Hanerau-Hademarschen, DE
• Elisabeth Perzborn · Wuppertal, DE
• Romanis Fruchtmann · Cologne, DE
• Christian Kohlsdorfer · Lechenich, DE
• Reiner Muller-Peddinghaus · Bensberg, DE
• Pia Theisen · Bensberg, DE

Key dates

• Filing date: May 19, 1989
• Grant date: Nov 13, 1990
• Expiry date: May 19, 2009

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D215/18
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Leucotriene synthesis inhibiting substituted 4-(quinolin-2-yl-methoxy)phenyl-acetic acid derivatives of the formula ##STR1## R.sup.1 --represents a group of the formula ##STR2## wherein Y--represents a group of the formula ##STR3## Z--represents norbornyl, or represents a group of the formula ##STR4## and A and B are identical or different and denote hydrogen, lower alkyl or halogen, and salts thereof.