Oxazolidinones

US4970217A · kind A · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Helmut Prucher · Heppenheim, DE
• Henning Bottcher · Darmstadt, DE
• Rudolf Gottschlich · Reinheim, DE
• Klaus-Otto Minck · Ober-Ramstadt, DE
• Anton Haase · Bogen, DE
• Christoph Seyfried · Seeheim-Jugenheim, DE

Key dates

• Filing date: Jul 15, 1988
• Grant date: Nov 13, 1990
• Expiry date: Jul 15, 2008

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Novel oxazolidinones of the formula I ##STR1## Z is O or S, R.sup.1 and R.sup.2 are each phenyl or benzyl radicals which are unsubstituted or mono- or disubstituted by alkyl, alkoxy, alkylthio, alkylsulfinyl and/or alkylsulfonyl having each 1-4 C atoms, alkanoyloxy and/or alkanoylamino having each 1-6 C atoms, F, Cl, Br, OH and/or CF.sub.3 or are heteroaryl radicals containing 1-4 heteroatoms and R.sup.3 and R.sup.4 are each H, alkyl or alkoxy having each 1-4 C atoms or are F, Cl, Br, OH or CF.sub.3, and also their salts have effects on the central nervous system, in particular neuroleptic effects.