Patent · US Expired

2-(piperazinyl)-2-oxoethylene-substituted flavonoid compounds

US4970301A · kind A · utility

10Cited by
6References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 29, 1988
Grant dateNov 13, 1990
Priority date
Expiry dateNov 29, 2008

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H17/07
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compound of general formula I: ##STR1## in which: A is a single or double bond, PA0 R.sub.1 and R.sub.3, which may be identical or different, are each a hydrogen atom, an alkoxycarbonylmethylene radical of formula --CH.sub.2 CO.sub.2 R.sub.4 (in which R.sub.4 denotes an alkyl radical having 1 to 5 carbon atoms) or a radical of formula W: ##STR2## (in which n is equal to 0 or 1 and R.sub.5, R.sub.6 and R.sub.7, which may be identical or different, are each a hydrogen or halogen atom, a hydroxyl radical, a trifluoromethyl radical, a lower alkyl radical containing 1 to 5 carbon atoms or an alkoxy radical containing 1 to 5 carbon atoms), PA0 R.sub.2 is a hydrogen atom, an alkoxycarbonylmethylene radical of formula --CH.sub.2 CO.sub.2 R.sub.4, a radical of formula W, or a .beta.-glucose or rutinose molecule linked to the oxygen to which it is attached with a glycoside bond, PA0 on condition, however, that at least either R.sub.1 or R.sub.2 or R.sub.3 always denotes a radical of formula W, and their addition salts with a pharmaceutically acceptable inorganic or organic acid.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.