Production of antibodies using a mixture of strains of E. coli collectively expressing type I pili, CFA I pili, CFA II pili and K88 pili
US4971794A · kind A · utility
9Cited by
5References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 19, 1986 |
| Grant date | Nov 20, 1990 |
| Priority date | — |
| Expiry date | Nov 19, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/849
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Antibodies are produced by hyperimmunizing a mammal, such as cow, with a vaccine derived from E. coli bacteria. The bacterial strains in the vaccine are selected on the basis of their virulence characteristics, especially adhesion factors (pili), associated with gastroenteric disease in humans. The antibodies can be recovered from the mammal's milk or serum, and used in human foods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.