Patent · US Expired

Process for the preparation of quinolonecarboxylic acids which can be administered parenterally

US4973590A · kind A · utility

9Cited by

4References

2Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Michael Preiss · Leinfelden, DE
Ulrich Schorsch · Goldkronach, DE
Arthur Haaf · Wuppertal, DE
Paul Naab · Bad Reichenhall, DE
Rudolf Zerbes · Wuppertal, DE

Key dates

Filing date	Apr 15, 1988
Grant date	Nov 27, 1990
Priority date	—
Expiry date	Apr 15, 2008

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P31/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Known quinolone carboxylic acid derivatives of the formula ##STR1## are treated so as to become readily administrable parenterally, the treatment comprising dissolving the active compound using an acid, allowing the solution to stand for about 0.15 to 150 hours at a temperature from room temperature to the boiling point of the solution, filtering the solution, precipitating the active compound from the solution using a basic reagent, and converting the precipitated active compound into a form which can be administered parenterally.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.