Peptide fragments containing HP and LP cross-links
US4973666A · kind A · utility
45Cited by
3References
1Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Nov 6, 1987 |
| Grant date | Nov 27, 1990 |
| Priority date | — |
| Expiry date | Nov 6, 2007 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/834
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for assaying bone resorption rates by quantitating the concentration of peptide fragments derived from bone collagen, found in a body fluid. The method includes immunometric assay, fluorometric assay and electrochemical titration. The structure of specific peptide fragments having 3-hydroxypyridinium cross-links found in urine of Paget's disease patients and procedures for making monoclonal antibodies is also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.