Process for preparing 3-hydroxy 2-keto acids
US4973747A · kind A · utility
1Cited by
3References
16Claims
0Family size
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Key dates
| Filing date | Aug 15, 1989 |
| Grant date | Nov 27, 1990 |
| Priority date | — |
| Expiry date | Aug 15, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C51/31
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process has now been discovered by which an intermediate in preparation of antibiotics ##STR1## may be directly derived from the substrate ##STR2## by treatment with aqueous solutions of MHCO.sub.3 and MOH, wherein: R.sup.1, R.sup.2 and R.sup.3 are each independently alkyl, alkenyl, alkynyl, substituted alkyl, substituted alkenyl, substituted alkynyl, aryl, or substituted aryl; PA1 M is alkali metal (such as Na, Li, or K); and PA1 X is halogen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.