Microbial transformation product of L-683,590
US4975372A · kind A · utility
5Cited by
1References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 13, 1989 |
| Grant date | Dec 4, 1990 |
| Priority date | — |
| Expiry date | Jan 13, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/826
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described is a new immunosuppressant, L-685,487, a monodemethylated rearranged derivative of L-683,590, produced under fermentation conditions utilizing the microorganism, unidentified Actinomycete (Merck Cultrue Collection MA 6474) ATCC No. 53828. The macrolide immunosuppressant is useful in preventing human host rejection of foreign organ transplants, e.g. bone marrow and heart transplants.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.