Patent · US Expired

Soluble phosphorylated glucan: methods and compositions for wound healing

US4975421A · kind A · utility

23Cited by
10References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 2, 1988
Grant dateDec 4, 1990
Priority date
Expiry dateDec 2, 2008

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC08B37/0024
  • WIPO fieldMacromolecular chemistry, polymers
  • WIPO sectorChemistry

Abstract

A new class of soluble phosphorylated glucans is described as well as the process for making the same. According to one embodiment, the soluble phosphorylated glucan is derived from the yeast Saccharomyces cerevisiae. The soluble phosphorylated glucans are useful for promoting the wound healing process. The soluble phosphorylated glucans are also useful for prophylactic and therapeutic applications against neoplastic, bacteria, viral, fungal and parasitic diseases. The soluble phosphorylated glucans are used either alone or in combination with a known antimicrobial agent for prophylactic and therapeutic antimicrobial applications. Additionally, they may be administered either alone or as a non-toxic adjuvant, in combination with chemotherapy. The soluble phosphorylated glucans are also useful for stimulating macrophage cells, either in vivo or in vitro, to produce a cytotoxic/cyctostatic factor effective against cancer cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.