Isomers of 1-azabicyclo(2.2.2)oct-3-yl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-5-nitropyridine-3-carboxylate
US4975437A · kind A · utility
1Cited by
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8Claims
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Assignee
Inventors
Key dates
| Filing date | Dec 14, 1989 |
| Grant date | Dec 4, 1990 |
| Priority date | — |
| Expiry date | Dec 14, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D453/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The four stereoisomers are disclosed having the formula: ##STR1## in which the asymmetric centers a and b are the same or different. The compounds are derived from the (+) and (-) alcohols and the (+) and (-) dihydropyridines and have either the absolute R or S configuration. Also disclosed are pharmaceutical compositions comprising an effective amount of the compounds in a pharmaceutically acceptable carrier and methods for producing cardiotonic activity using the compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.