6-amino-2-benzothiazolesulfonamide and topical treatment compositions and method for glaucoma
US4975448A · kind A · utility
4Cited by
1References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 4, 1985 |
| Grant date | Dec 4, 1990 |
| Priority date | — |
| Expiry date | Apr 4, 2005 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/80
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A topical composition for eye treatment of glaucoma, comprising a small but pharmaceutically effective amount of an analog of benzothiazole-2-sulfonamide. The most preferred compound is 6-amino-2-benzothiazolesulfonamide. The invention also relates to a method of topically treating glaucoma with eye drops to reduce intraocular pressure. Finally, disclosed is a method of synthesis of the preferred and highly effective benzothiazole-2-sulfonamide analogs, particularly the 6-amino-2-benzothiazolesulfonamide compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.