Method for the separation of biological macromolecules by chromatography
US4976865A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 22, 1987 |
| Grant date | Dec 11, 1990 |
| Priority date | — |
| Expiry date | Oct 22, 2007 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D15/1892
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A method for allowing biological macromolecules contained in a solution to be separated by selective absorption comprising supplying with a solution each stage (3, 4) of a column containing a selective chromatographic resin specific to the macromolecules to be separated, so as to fluidize the beds of resin at each stage, each stage being provided at its base with a perforated distribution system (5) characterized by a percentage of open sections between 0.2% and 10%, a mean diameter of the said open sections greater than approximately 300 microns and between 2G.sub.m and 20G.sub.m, where G.sub.m is the mean granulometry of the resin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.