Method for the determination of anti-P. falciparum sporozoite antibodies in human blood
US4977079A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 17, 1987 |
| Grant date | Dec 11, 1990 |
| Priority date | — |
| Expiry date | Dec 17, 2007 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/828
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An immunoenzimatic method is disclosed for the detection and the measurement of anti-P. falciparum sporzoite antibodies in human blood and/or in its derivatives, which operates with a synthetic antigen-enzyme conjugate capable of forming with the antisporozoite antibodies a stable antibody-synthetic antigen-enzyme complex, and one or more proteins absorbed and/or covalently linked to a solid support, which eagerly bind the antisporozoite antibody of said complex. The method, thanks to its simpleness, specificity and rapidity, is particularly useful in epidemiologic investigations into malaria and into the efficacy of an antimalarial vaccine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.