Novel tricyclic derivatives which are agonists of cholinergic receptors, and drugs in which they are present
US4977152A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 25, 1990 |
| Grant date | Dec 11, 1990 |
| Priority date | — |
| Expiry date | Jan 25, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to novel tricyclic derivatives which are agonists of cholinergic receptors and to drugs containing them. These derivatives have the following formula: ##STR1## in which: X represents a group (CH.sub.2).sub.n, n representing an integer equal to 2, 3 or 4, or alternatively a vinylene group or a methylvinylene group; PA0 R.sub.1 and R.sub.2, considered independently, represent hydrogen or a substituent occupying one of the free positions of the benzene ring and selected from the group comprising halogens, a lower alkyl group, a lower alkoxy group, a hydroxyl group, a thiol group, a nitro group and an optionally substituted amino group; PA0 Y represents oxygen, sulfur or a group --NH--; and PA0 R.sub.3 is an amino group Application: agonists of the cholinergic receptors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.