Piperidine derivative and therapeutic and preventive agents for arrhythmia containing same
US4977165A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 19, 1988 |
| Grant date | Dec 11, 1990 |
| Priority date | — |
| Expiry date | Aug 19, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/38
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A piperidine compound has the generic formula and is useful to treat arrhythmia. ##STR1## in which R.sup.1 is a lower alkyl and W is: ##STR2## X is --S--, --SO-- or --SO.sub.2 --, R.sup.2 is hydrogen or --(CH.sub.2).sub.n --Y, n is an integer of 1 to 5, Y is an aryl, pyridyl or a substituted pyridyl, X' is --CO-- or --CH(OH)--, PA0 p is an integer of 1 to 4, R.sup.12 is hydrogen or a lower alkyl, Y' is --(CH.sub.2).sub.m --A, m is 1 or 2, A is an aryl, a substituted aryl, pyridyl or a substituted pyridyl, R.sup.12 and Y may form a 5- or 6-membered ring or a 5- or 6-membered ring having one or more substituents and PA0 R.sup.22 is hydrogen, a halogen, a lower alkyl, a lower alkoxy or hydroxy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.