Method of treating anxiety and depression with 1-phenyl-2(1H,3H)-indolone psycho-therapeutic agents
US4977178A · kind A · utility
7Cited by
10References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 19, 1989 |
| Grant date | Dec 11, 1990 |
| Priority date | — |
| Expiry date | Jul 19, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D209/38
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Certain substituted 1-phenyl-3-(aminoalkylidene)-2(1H,3H)-indolones are highly potent gabaergic agents, valuable in the treatment of individuals suffering from schizophrenia or reversing the side effects of a previously or concurrently administered neuroleptic agent; or in the treatment of epilepsy. A wider class of substituted 1-phenyl-3-(aminoalkylidene)-2(1H,3H)-indolones, together with 1-phenyl-3-(2-pyrrolidinylidene)-2(1H,3H)-indolones, and homologs thereof, are valuable in the treatment of anxiety.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.