Conjugates in which a monovalent carboxylic ionophore is associated by means of a covalent bond with a macromolecule, their use as immunotoxin potentiators and the intermediate activated ionophores
US4977280A · kind A · utility
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3Claims
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Key dates
| Filing date | Dec 27, 1989 |
| Grant date | Dec 11, 1990 |
| Priority date | — |
| Expiry date | Dec 27, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/01
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to conjugates in which a monovalent carboxylic ionophore is associated by means of a covalent bond with a macromolecule chosen from antibodies, fragments of antibodies, proteins such as peptide hormones or human proteins, and peptide ligands. It also relates to the activated ionophores. These conjugates are suitable as immunotoxin potentiators.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.