Patent · US Expired

Treatments employing vasoconstrictive substances in combination with cytotoxic agents for introduction into cellular lesion areas

US4978332A · kind A · utility

48Cited by
10References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 28, 1987
Grant dateDec 18, 1990
Priority date
Expiry dateSep 28, 2007

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P35/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A pharmaceutical composition and method of treating cellular disorders involving abnormal solid cellular growths which comprises administering a pharmaceutical composition containing cytotoxic agents in combination with a vasoconstrictive drug. Enhanced effectiveness of the composition is observed, with reduced cytotoxic effects on cells distant from the site of introduction. Agents may be included to enhance therapeutic gain and reduce adverse affects to normal tissue.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.