Cytophaga-derived immunopotentiator
US4978622A · kind A · utility
117Cited by
2References
8Claims
0Family size
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Key dates
| Filing date | Sep 1, 1989 |
| Grant date | Dec 18, 1990 |
| Priority date | — |
| Expiry date | Sep 1, 2009 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/55594
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Substantially pigment-free gliding bacteria adjuvant (GBA) is isolated from medium in which Cytophaga strain GB-2 has been cultured by extraction with acetone to remove pigment, enzymatic digestion and filtration to remove residual protein and nucleic acids, and affinity chromatography to remove residual lipopolysaccharide. This pure form of GBA shows unexpectedly high specific immunopotentiating activity relative to crude GBA.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.