Sucrose-6-ester chlorination
US4980463A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 18, 1989 |
| Grant date | Dec 25, 1990 |
| Priority date | — |
| Expiry date | Jul 18, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H5/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the chlorination of sucrose-6-esters to produce 6',4,1'-trichlorosucrose-6-esters which comprises the steps of: PA1 (a) adding at least seven molar equivalents of an acid chloride to a reaction mixture containing a sucrose-6-ester and a tertiary amide to form initially a chloroformiminium chloride salt which subsequently forms a complex with the hydroxyl groups of the sucrose-6-ester; PA1 (b) subjecting the reaction mixture product of step (a) to an elevated temperature not higher than about 85.degree. C. for a period of time sufficient to produce a mixture of chlorinated sucrose-6-ester products consisting essentially of 6'-chlorosucrose-6-ester, 4,6'-dichlorosucrose-6-ester, and 1',6'-dichlorosucrose-6-ester; and PA1 (c) subjecting the reaction mixture product of step (b) to an elevated temperature not higher than about 125.degree. C. for a period of time sufficient to produce a chlorinated product consisting essentially of 1',4,6'-trichlorosucrose-6-ester.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.