Coincidence arbitration in a flow cytomery sorting system
US4981580A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | May 1, 1989 |
| Grant date | Jan 1, 1991 |
| Priority date | — |
| Expiry date | May 1, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S209/906
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A coincidence arbitration system for a sorting cytomteter which detects and sorts particles using a flow chamber and a stream of droplets. Those droplets containing selected particles are sorted by selectively applying a charge thereto and passing the droplets through deflection plates. After detection, the particle data is delayed and analyzed to make sort decisions. The delay is for a period of one and one fourth droplet time periods less than the time the particle is formed into a droplet. At the time the command is issued creating the charge on the droplet to be formed, the coincidence arbitration circuit looks four quarter droplet times ahead and behind of the event to determine whether a coincidence is occurring, and if so, whether the coincidence is with a similar type of particle or a different type of particle. Based on this information, appropriated sort or no-sort commands are issued.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.