Oligonucleotides with modified phosphate and modified carbohydrate moieties at the respective chain termini
US4981957A · kind A · utility
418Cited by
2References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 18, 1985 |
| Grant date | Jan 1, 1991 |
| Priority date | — |
| Expiry date | Jul 18, 2005 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to novel oligonucleotides, the process for their preparation and their biological uses as mediators of the action of interferon. The oligonucleotides according to the invention have the formula: ##STR1## in which Y and T are identical or different and represent particularly O, S, Z and W are identical or different and represent particularly O, S, one at least of the elements Y and Z being different from oxygen, X represents particularly --CHOHCH.sub.2 OH, .SIGMA. is a whole number equal to or greater than 2, A represents adenine or one of its derivatives. These oligonucleotides have antiviral use.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.