N-(4-(3-aminopropyl)aminobutyl)-2-(.omega.-gua nidino-fatty-acid-amido(-2-substituted-ethanamide, salt thereof, and process for preparation thereof
US4983328A · kind A · utility
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Key dates
| Filing date | Mar 15, 1988 |
| Grant date | Jan 8, 1991 |
| Priority date | — |
| Expiry date | Mar 15, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P13/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
N-[4-(3-Aminopropyl)aminobutyl]-2-(.omega.-guanidino-fatty acid-amido)-2-substituted-ethanamides represented by the general formula ##STR1## wherein Y represents --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH or ##STR2## R represents a hydrogen atom, an alkyl group of 1 to 4 carbon atoms which may have a hydroxyl group as substituent, or a benzyl group, and n is an integer of from 1 to 8, provided that when Y is ##STR3## and n is 4, R represents the groups other than the hydrogen atom; salt thereof having antitumor activity in experimental animal tumors and a process for the preparation thereof is provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.