Aqueous steroid formulations for nasal administration
US4983595A · kind A · utility
22Cited by
2References
1Claims
0Family size
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Key dates
| Filing date | Sep 20, 1988 |
| Grant date | Jan 8, 1991 |
| Priority date | — |
| Expiry date | Sep 20, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/57
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A non-stinging aqueous anti-inflammatory steroid formulation suitable for intranasal administration comprises: an anti-inflammatory steroid in an amount between about 0.01% and about 0.05% (w/v); propylene glycol in an amount between about 2% and about 10% (w/v); PEG 400 in an amount between about 10% and about 25% (w/v); polysorbate 20 in an amount between about 1% and about 4% (w/v); an effective amount of a preservative; an effective amount of a stabilizer; an effective amount of an antioxidant; water; and pH buffering agent sufficient to adjust the pH of the resulting solution to between about 3.5 and about 7.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.