Patent · US Expired

3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid derivatives and their preparation

US4983596A · kind A · utility

5Cited by
1References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 4, 1989
Grant dateJan 8, 1991
Priority date
Expiry dateMay 4, 2009

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/55
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention relates to a compound of antimicrobial activity, of the formula: ##STR1## in which R.sup.1 is carboxy or protected carboxy, PA1 R.sup.2 is hydroxy(lower)alkyl or protected hydroxy(lower)alkyl, PA1 R.sup.3 is hydrogen or lower alkyl, PA1 R.sup.4 is 2-fluoroethyl, 2-chloroethyl, 2-fluoropropyl or 4-fluorobutyl, PA1 R.sup.5 is hydrogen, lower alkanimidoyl, unsubstituted lower cycloalkenyl or substituted by a group consisting of oxo and amino, or imino-protective group, and PA1 A is lower alkylene, or pharmaceutically acceptable salts thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.