Derivatives of cyclic amino acids, agents containing them, and the use thereof

US4983623A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Rainer Henning · Tokyo, JP
• Hansjorg Urbach · Kronberg, DE
• Franz Hock · Dieburg, DE

Key dates

• Filing date: Dec 13, 1988
• Grant date: Jan 8, 1991
• Expiry date: Dec 13, 2008

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D453/06
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to derivatives of cyclic amino acids of the general formula ##STR1## in which R.sup.1 denotes hydrogen, alkyl, alkenyl or (subst.) aryl, PA0 R.sup.2 is hydrogen, alkyl, hydroxyl, alkoxy, (subst.) aryl, (subst.) aryloxy or (subst.) aroyl, or R.sup.1 and R.sup.2 together represent (subst.) benzylidene, or R.sup.1 and R.sup.2, together with the carbon atom carrying them, represent (subst.) cycloalkyl, R.sup.3 denotes hydrogen, hydroxymethyl, formyl, (subst.) alkenyl, (subst.) carboxycarbonyl, (subst.) carbamoylcarbonyl or (subst.) trifluoromethylcarbonyl, A represents a cyclic amino acid, X denotes oxygen, imino or N-alkylimino, m is 0-5 and n is 0 or 1, to a process for the preparation thereof, to agents containing them, and to the use thereof.