Method of deprotection of 3-amino azetidinones
US4983732A · kind A · utility
6Cited by
2References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 21, 1989 |
| Grant date | Jan 8, 1991 |
| Priority date | — |
| Expiry date | Sep 21, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method for preparing 2-amino-.beta.-lactams which are substituted by readily-removed protecting groups is provided. According to this invention, an acyl-2-amino-.beta.-lactam is further acylated with a different acyl group and is subsequently treated with base to provide a protected 2-amino .beta.-lactam with allyloxycarbonyl, t-butoxycarbonyl, naphthyloxycarbonyl, trichloroethyloxycarbonyl, p-nitrobenzyloxycarbonyl, benzhydryloxycarbonyl, p-methoxybenzyloxycarbonyl, or o-nitrobenzyloxycarbonyl.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.