Preparation of alcohol-extended and amine-extended piperazines
US4983735A · kind A · utility
16Cited by
1References
26Claims
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Key dates
| Filing date | Jul 20, 1988 |
| Grant date | Jan 8, 1991 |
| Priority date | — |
| Expiry date | Jul 20, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/13
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for preparing alcohol-extended and amine-extended piperazines comprising contacting a difunctional aliphatic alcohol with a reactant amine, wherein at least one of the aliphatic alcohol or the reactant amine contains a piperazine moiety, in the presence of a catalyst containing a tungsten heteropoly acid. For example, monoethanolamine reacts with piperazine in the presence of a 12-tungstophosphoric acid catalyst to yield predominantly N-(2-aminoethyl)piperazine, which is an amine-extended piperazine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.