Process for the enzymatic resolution of the optical isomers of racemic ester derivatives of 3-mercapto-2-alkyl-propionic acid
US4985366A · kind A · utility
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Key dates
| Filing date | May 30, 1989 |
| Grant date | Jan 15, 1991 |
| Priority date | — |
| Expiry date | May 30, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P41/004
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The biotechnological resolution by means of stereoselective enzymatic thio-transesterification of the racemic mixture of the optical isomers of the compounds of formula (I): ##STR1## wherein: R, R' and R", alike or different form one another, represent a linear alkyl group of from C.sub.1 to C.sub.4, in the presence of an alcohol and an enzyme capable of selectively causing the reaction of thio-transesterification of the (L)-isomer to take place, with the (D)-isomer remaining substantially unchanged, and being then separated by means of per se known techniques.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.