Patent · US Expired

1,7-annelated indolecarboxylic acid esters and -amides

US4985420A · kind A · utility

16Cited by
1References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 7, 1988
Grant dateJan 15, 1991
Priority date
Expiry dateDec 7, 2008

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to new 1,7-annelated esters and amides of indolecarboxylic acids having general formula 2, ##STR1## wherein the symbols have the meanings given in the specification. The compounds and their salts are very strong and selective antagonists of "neuronal" 5-hydroxytryptamine (5-HT) receptors, and can be used for the treatment of symptoms which are caused by over-stimulation of these receptors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.