1-aryloxy-2,3,4,5-tetrahydro-3-benzazepines and anti-depressant use thereof
US4988690A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 14, 1982 |
| Grant date | Jan 29, 1991 |
| Priority date | — |
| Expiry date | Jun 14, 2002 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/26
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to 1-aryloxy-2,3,4,5-tetrahydro-3-benzazepines of the formula ##STR1## wherein Y is the same or different and is hydrogen and lower alkoxy; X is hydrogen, halogen, lower alkyl, lower alkoxy, CF.sub.3, NO.sub.2, CN and NH.sub.2 ; R is hydrogen, lower alkyl, cycloalkyllower alkyl, ##STR2## Ar lower alkyl of the formula -alkylene ##STR3## where Z is hydrogen, lower alkyl, lower alkoxy, halogen, CF.sub.3, NO.sub.2 and NH.sub.2 ; and an alkylene amine of the formula ##STR4## where R.sub.1 and R.sub.2 are the same of different and are hydrogen and lower alkyl, and the pharmaceutically acceptable acid addition salts thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.