Patent · US Expired

16.alpha.-methylation process

US4990612A · kind A · utility

18Cited by
12References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 5, 1988
Grant dateFeb 5, 1991
Priority date
Expiry dateDec 5, 2008

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07J71/0015
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Disclosed is a process for the production of a .DELTA..sup.17(20) -steroid of the formula ##STR1## which comprises starting with a 16-unsaturated corticoid of the formula ##STR2## and contacting the 16-unsaturated corticoid (I) with a methylating agent in the presence of a copper catalyst and a silylating agent.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.