Tissue plasminogen activator A-chain/urokinase B-chain hybrid protein
US4992274A · kind A · utility
17Cited by
4References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 22, 1988 |
| Grant date | Feb 12, 1991 |
| Priority date | — |
| Expiry date | Feb 22, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A fibrinolytically active hybrid protein which comprises one chain of a 2-chain protease linked to a chain of a different 2-chain protease, or to the same chain of the same protease, at least one of the chains in the hybrid protein being derived from a fibrinolytically active protease, such that the hybrid protein has a catalytic site essential for fibrinolytic activity which is optionally blocked by a removable blocking group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.