Vectors and compounds for direct expression of activated human protein C
US4992373A · kind A · utility
43Cited by
4References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 4, 1987 |
| Grant date | Feb 12, 1991 |
| Priority date | — |
| Expiry date | Dec 4, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/50
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method for the direct recombinant production of activated protein C is described. DNA compounds, vectors, and transformants useful in the method are also disclosed. The method involves transformation and culture of a host cell with a recombinant DNA vector that encodes a protein C molecule in which the activation peptide is replaced with a cleavage sequence for a cell associated protease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.