Polycyclic ether antibiotics
US4992423A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 8, 1988 |
| Grant date | Feb 12, 1991 |
| Priority date | — |
| Expiry date | Feb 8, 2008 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/825
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A new acidic polycyclic ether antibiotic UK-58,852 has the formula: ##STR1## wherein R and R.sup.1 are both hydrogen, and can be prepared by the submerged aerobic propagation in aqueous nutrient media of Actinomadura sp. ATCC 39697. The antibiotic and its cationic salts are active against a variety of microorganisms and are effective in controlling coccidiosis, enteritis, swine dysentery and theileriosis as well as being effective in promotion of growth and/or improving efficiency of feed utilization is swine and ruminants. Two minor components, where R is H and R.sup.1 is CH.sub.3 and wherein R and R.sup.1 are both CH.sub.3, have also been isolated from the fermentation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.