Antiparasitic avermectin derivatives
US4992424A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 7, 1989 |
| Grant date | Feb 12, 1991 |
| Priority date | — |
| Expiry date | Mar 7, 2009 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P33/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Broad spectrum antiparasitic agents of formula (I) having utility as anthelmintics, ectoparasiticides, insecticides, acaricides and animal growth promotants ##STR1## wherein Y is a single bond or a double bond; R.sup.1 is OH; provided that when Y is a single bond R.sup.1 is present and when Y is a double bond R.sup.1 is absent; R.sup.2 is .dbd.CH.sub.2 or a group of the formula --(X)--C(R.sup.5).dbd.CHR.sup.6 ; R.sup.3 is H or CH.sub.3 ; R.sup.5 and R.sup.6 are both H; R.sup.5 is H and R.sup.6 is C.sub.1 -C.sub.3 alkyl; or one of R.sup.5 and R.sup.6 is H and the other is C.sub.2 -C.sub.6 alkoxycarbonyl, phenyl, substituted phenyl, heteroaryl or substituted heteroaryl; and X is a direct bond or an alkylene group having from 2 to 6 carbon atoms which may be straight or branched-chain; with the proviso that R.sup.5 and R.sup.6 are not both hydrogen when X is --CH(CH.sub.3)CH.sub.2 --; processes and intermediates therefor, and compositions thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.