7-(substituted)cycloalkylamino-1 -(substituted)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids
US4992449A · kind A · utility
4Cited by
17References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 1, 1990 |
| Grant date | Feb 12, 1991 |
| Priority date | — |
| Expiry date | Feb 1, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel antibacterial compounds of the formula: ##STR1## in which R.sub.1 is alkyl (C.sub.1 -C.sub.4), cycloalkyl (C.sub.3 -C.sub.6), alkoxy (C.sub.1 -C.sub.4), alkylamino (C.sub.1 -C.sub.3), vinyl, phenyl, benzyl, --CH.sub.2 CH.sub.2 F or mono or polysubstituted phenyl (wherein the substituent is halogen, CF.sub.3 or OCH.sub.2 F); n is an integer of from 1 to 4; and R.sub.2 is cis or trans hydroxy, amino, mono or disubstituted alkyl (C.sub.1 -C.sub.3) amino and the pharmacologically accepted salts thereof are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.