Thiazolidin-4-one derivatives useful for treating diseases caused by platelet activating factor
US4992455A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 19, 1988 |
| Grant date | Feb 12, 1991 |
| Priority date | — |
| Expiry date | May 19, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Thiazolidin-4-one derivative represented by the folowing general formula (I) and acid addition salts thereof ##STR1## wherein; R.sup.1 and R.sup.2 are the same or different and denote each PA1 (i) a residue represented by the general formula EQU --A--R.sup.4 PA1 wherein, A denotes a single bond, C.sub.1 -C.sub.8 alkylene, C.sub.2 -C.sub.8 alkenylene, or C.sub.2 -C.sub.8 alkynylene and R.sup.4 denotes hydrogen, C.sub.1 -C.sub.12 alkyl, C.sub.2 -C.sub.8 alkenyl, C.sub.3 -C.sub.8 cycloalkyl, or C.sub.1 -C.sub.6 haloalkyl, or PA1 (ii) a residue represented by the general formula EQU {(CH.sub.2).sub.n O}.sub.m {(CH.sub.2).sub.n' O}B--R.sup.5 PA1 wherein, B denotes a single bond or C.sub.1 -C.sub.6 alkylene, R.sup.5 denotes hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.8 alkenyl, C.sub.3 -C.sub.8 cycloalkyl, substituted silyl, or substituted or unsubstituted aryl, n and n' denote each an integer of 2 to 4, m denotes an integer of 1 to 3, and m' denotes an integer of 0 to 2; and PA0 R.sup.3 denotes hydrogen, C.sub.1 -C.sub.2 alkyl, allyl, 2-propynyl, or a residue represented by PA1 (a) the general formula EQU --CH.sub.2).sub.l R.sup.6 PA1 wherein, R.sup.6 denotes halogen, an aryl group…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.