Renin inhibitors containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues
US4992562A · kind A · utility
1Cited by
5References
2Claims
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Key dates
| Filing date | Mar 22, 1990 |
| Grant date | Feb 12, 1991 |
| Priority date | — |
| Expiry date | Mar 22, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/0227
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A series of novel polypeptide derivatives, containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues, which are useful for inhibiting the angiotensinogen-cleaving action of the enzyme renin. Particularly valuable precursors for many of these compounds are certain other 5-amino-2,5-disubstituted-4-hydroxypentanoic acid derivatives.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.