N-[[6 -methoxy-5-(trifluoromethyl)-1-naphthalenyl]-thioxomethyl]-N-methylglycin e S-oxide and the amide thereof
US4994381A · kind A · utility
1Cited by
13References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 20, 1989 |
| Grant date | Feb 19, 1991 |
| Priority date | — |
| Expiry date | Mar 20, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/897
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are N-[[6-methoxy-5-(trifluoromethyl)-1-naphthalenyl]-thioxmethyl]-N-methylgly cine S-oxide (tolrestat S-oxide) and the amine thereof and methods of their preparation. The S-oxides are new aldose reductase inhibitors useful for the treatment or prevention of diabetic complications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.