Dopaminergic compounds
US4994486A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 22, 1989 |
| Grant date | Feb 19, 1991 |
| Priority date | — |
| Expiry date | Dec 22, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2603/93
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel compounds of Formula (I): ##STR1## or pharmaceutically acceptable salts, esters and amides thereof, wherein A is O, C, CH or CH.sub.2, n is 0 or 1, and the dotted line is a single bond when A is O or CH.sub.2 and a double bond when A is CH or when n=0, A is C and PA0 R.sub.6 and A taken together form a nitrogen-containing heterocycle; PA0 R is hydrogen, lower alkyl or a readily cleavable group; PA0 R.sub.1 is selected from hydrogen, halogen, lower alkyl, haloalkyl and lower alkoxy; PA0 R.sub.2 is selected from hydrogen, halogen, lower alkyl and haloalkyl or, taken together with R.sub.8, forms a fused ring; PA0 R.sub.3 is hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, aryl or arylalkyl or, taken together with R.sub.4, forms a spirocycloalkyl or, taken together with R.sub.5, forms a fused cycloalkyl; PA0 R.sub.4 is hydrogen or alkyl or, taken together with R.sub.3, forms a spirocycloalkyl; PA0 R.sub.5 is hydrogen or alkyl or, taken together with R.sub.3, forms a fused cycloalkyl; PA0 R.sub.6 is hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl or arylalkyl or, taken together with A when A is C and when n is 0, forms a fused nitrogen-containing heterocycle or, taken together with R.…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.