Patent · US Expired

Preparation of pharmaceutical or cosmetic dispersions

US4996004A · kind A · utility

108Cited by

8References

6Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Manfred Bucheler · Overath, DE
Hans Gehringer · Cologne, DE
Bernd Klinksiek · Bensberg, DE
Bernd Koglin · Bensberg, DE

Key dates

Filing date	Mar 15, 1989
Grant date	Feb 26, 1991
Priority date	—
Expiry date	Mar 15, 2009

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S516/925
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to a process for the preparation of fine-particled, stable, pharmaceutical or cosmetic dispersions consisting of an aqueous phase and an organic phase which is insoluble or not completely soluble in water (oily phase) in which a pre-emulsion is prepared from the two phases by known emulsifying methods and in then pumped through a jet disperser, the temperature, the proportion of the aqueous and organic phases, and the pressure at the jet disperser being adjusted so that phase inversion of the emulsion is effected in the jet disperser at the same time as homogenization and fine dispersion, and in the course of which all the pressure energy is consumed in the dispersing zone and the dispersion leaves as a non-directional stream.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.