Method for enhancing the lowering of plasma cholesterol levels
US4997658A · kind A · utility
13Cited by
13References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 21, 1988 |
| Grant date | Mar 5, 1991 |
| Priority date | — |
| Expiry date | Nov 21, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The instant invention is directed to a method for enhancing the lowering of plasma cholesterol level in a subject in need thereof which comprises the time-controlled administration of a nontoxic therapeutically effective amount of an HMG-CoA reductase inhibitor to said subject which surprisingly affords an equivalent or improved reduction of plasma cholesterol levels while significantly reducing the amount of HMG-CoA reductase inhibitor circulating in the bloodstream of the subject as compared to the same parameters when the oral administration of a conventional rapid release dosage form is utilized.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.