Vectors for gene insertion into avian germ line
US4997763A · kind A · utility
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4Claims
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Key dates
| Filing date | Jul 31, 1987 |
| Grant date | Mar 5, 1991 |
| Priority date | — |
| Expiry date | Jul 31, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/13043
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A stable, substantially nononcogenic vector having a cloning site for the convenient insertion of a gene of interest has been constructed by recombinant technology from an avian retrovirus. The construct is derived from Rous sarcoma virus and the cloning site is a replacement for the csr oncogene. This vector is useful for ferrying selected, expressible genes into avian germ cells for incorporation into the germ line. The vector is also useful for inserting and expressing foreign genes in somatic avian cells both in vivo and in vitro.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.