Compounds with a psychotropic action, agents containing them, and the use thereof for the treatment and prophylaxis of disorders of the central nervous system

US4999370A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Wolfgang Ruger · Alfeld, DE
• Hansjorg Urbach · Kronberg, DE
• Rainer Henning · Tokyo, JP
• Jens Stechl · Frankfurt am Main, DE
• Patricia Usinger · Eppstein, DE
• Franz Hock · Dieburg, DE

Key dates

• Filing date: Jan 25, 1989
• Grant date: Mar 12, 1991
• Expiry date: Jan 25, 2009

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/20
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds with a psychotropic action, agents containing them, and the use thereof for the treatment and prophylaxis of disorders of the central nervous system. The invention relates to the use of angiotensin converting enzyme inhibitors as pharmaceuticals with a psychotropic, especially anxiolytic, action, to agents containing them, and to the use thereof for the treatment or prophylaxis of disorders of the central nervous system, especially of anxiety states. The invention also relates to new compounds of the formula ##STR1## in which R.sup.2 denotes hydrogen or ethyl, and R.sup.3 denotes n-octyl, to processes for the preparation thereof, to agents containing them, and to the use thereof as pharmaceuticals.