Process for the preparation of .alpha.,.alpha.,.beta.-1-trifluoro-1-olefinic derivatives
US4999429A · kind A · utility
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1References
11Claims
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Key dates
| Filing date | Nov 13, 1989 |
| Grant date | Mar 12, 1991 |
| Priority date | — |
| Expiry date | Nov 13, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C49/80
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Aryl difluoromethyl sulfone adds to aldehydes under phase transfer conditions to give novel substituted alcohols of the general formula EQU RCH(OH)CF.sub.2 SO.sub.2 Ar (I) wherein R is an aryl, cycloaliphatic, sec- or tert-aliphatic, or heterocyclic group and Ar is an aryl group. The substituted alcohols of formula I are of particular utility as intermediates in the synthesis of a variety of useful end products. For example, the products of formula I may be utilized in desulfonylation reactions, oxidation reactions and fluorination reactions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.