Aryl-substituted thiophene 3-ols, derivatives and analogs useful as lipoxgenase inhibitors
US4999436A · kind A · utility
4Cited by
12References
4Claims
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Key dates
| Filing date | Aug 22, 1989 |
| Grant date | Mar 12, 1991 |
| Priority date | — |
| Expiry date | Aug 22, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/80
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Aryl substituted thiophenes 3-ols, its dihydro derivatives, 1-oxide and 1,1-dioxide analogs, as well as aryl substituted furans, are 5-lipoxygenase inhibitors useful in the treatment of inflammation and other leukotriene-mediated diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.