Method for monitoring glucose
US5001054A · kind A · utility
502Cited by
14References
9Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jul 31, 1990 |
| Grant date | Mar 19, 1991 |
| Priority date | — |
| Expiry date | Jul 31, 2010 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/209163
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for monitoring the glucose level in a body fluid uses an apparatus which includes a conjugate of glucose oxidase and a fluorescent dye coated onto an optical fiber in contact with the body fluid, a source of excitation light and a fluorescence emission detector. Glucose is oxidized by oxygen in the body fluid causing a decrease in oxygen concentration at the enzyme. The fluorescent dye is sensitive to oxygen quenching so that, when the oxygen concentration decreases, fluorescence emission increases in direct proportion to the glucose concentration in the fluid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.