Calcification mitigation of bioprosthetic implants
US5002566A · kind A · utility
158Cited by
8References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 18, 1989 |
| Grant date | Mar 26, 1991 |
| Priority date | — |
| Expiry date | Apr 18, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S623/918
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Calcification resistant bioprosthetic implants are made from tanned biological materials, such as porcine heart valves, bovine pericardium, human dura mater or the like, which has been impregnated with a calcification-mitigating effective amount of a ferric and/or stannic salt. The impregnated biological materials and processes are particularly advantageous for the preparation of bioprosthetic heart valves. These implants have been found to be highly resistant to calcification in vivo.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.