Peptides representing epitopic sites for the major HTLV-I envelope protein, antibodies thereto, and uses thereof
US5003043A · kind A · utility
11Cited by
4References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 25, 1988 |
| Grant date | Mar 26, 1991 |
| Priority date | — |
| Expiry date | May 25, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/14022
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention discloses synthetic peptides and antibodies raised thereto wherein the synthetic peptides represent important epitopic sites recognized by the 0.5 .alpha. antibody, a human monoclonal antibody which can neutralize HTLV-I. Also, the uses of these peptides or antibodies thereto either alone or in combination with peptides representing the epitopic site for the predominant antibodies found in HTLV-I env seropositive sera as diagnostics, therapeutics and vaccines are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.